cobas® c 303 Analyzer
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System Overview
A fully automated, high-throughput photometric analyzer designed for in vitro quantitative and qualitative testing.
Throughput (Testing Capacity)
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Photometric only: Up to 450 tests/hour
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ISE only: Up to 450 tests/hour (or 150 samples/hour)
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Mixed mode (Photometric & ISE): Up to 750 tests/hour (300 photometric tests + 450 ISE tests/hour)
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HbA1c only: 225 tests/hour
Reagent Characteristics
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Reagent package type: cobas® c pack green
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Reagent loading/unloading: Manual
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Reagent identification: RFID (Radio Frequency Identification)
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The cobas® c 303 analyzer is an essential module of Roche’s cobas® pure integrated solutions, designed for in vitro diagnostics (IVD). It is a fully automated, high-throughput photometric analyzer for performing clinical chemistry and electrolyte testing. The cobas® c 303 combines both clinical chemistry and electrolyte testing capabilities within a compact footprint of just 1.2 m² (in chemistry-only configuration).
Engineered to deliver excellent performance and simplify daily laboratory workflows, the cobas® c 303 is part of the cobas® pure system, integrating clinical chemistry, immunoassay, and electrolyte testing into one compact platform. This system significantly reduces manual intervention, saving valuable operator time.
Key Features:
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Automatic Calibration (cobas® AutoCal): Reduces calibration workload by 56%, saving up to 105 hours annually, with automatic reagent lot calibration for most chemistry tests.
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Minimal Maintenance: Daily manual maintenance tasks take just 5 minutes.
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Ready-to-use Reagents: Utilizes cobas® c pack green reagents, requiring no preparation, mixing, waiting, or uncapping. These reagents are highly stable on the analyzer (average 137 days, with 57% stable for up to 6 months).
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Assay Integrity & Safety: Features include non-contact ultrasonic mixing to prevent contamination, thorough probe rinsing with deionized water after each sample, special cleaning programs for high-sensitivity assays, and automated detection of liquid levels, clots, and air bubbles. Automatic rerun and dilution functions ensure reliable results.
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Proven Reliability: The cobas® pure solution offers >99% uptime, backed by a track record of over 75,000 cobas analyzers installed worldwide.
Standardization and Efficiency:
As part of the cobas® pure integrated solution, the cobas® c 303 standardizes operations and results with other cobas solutions (such as cobas® pro), simplifying staff training and optimizing patient management. It also provides a broad test menu with over 230 clinically valuable assays.




